Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population
10/10/20161 分钟阅读
Abstract
Background: Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism is involved in DNA synthesis, DNA repair and DNA methylation. The functional polymorphism of MTHFR gene, C677T has been shown to impact various diseases and implicated as a risk factor for the development of various neurodegenerative disorders including glaucoma.
Post authors
Hamoud Al-Shahrani 1, Najwa Al-Dabbagh 1, Nourah Al-Dohayan 1, Misbahul Arfin 2, Mohammad Al-Asmari 2, Sadaf Rizvi 2, Abdulrahman Al-Asmari 3